![]() ![]() Register (ACFR) issues a regulation granting it official legal status.įor complete information about, and access to, our official publications Informational resource until the Administrative Committee of the Federal This prototype edition of theĭaily Federal Register on will remain an unofficial Each document posted on the site includes a link to theĬorresponding official PDF file on. The documents posted on this site are XML renditions of published Federal Register, and does not replace the official print version or the official It is not an official legal edition of the Federal Please see the DDW faculty disclosure index for a list of all other authors’ relevant financial disclosures.This site displays a prototype of a “Web 2.0” version of the dailyįederal Register. Presented at: Digestive Disease Week June 2-5, 2018 Washington, D.C.ĭisclosure: Sooklal reports no relevant financial disclosures. Sooklal, moderators and audience members pointed out a need for looking at these results in the light of comorbidities in the future, especially the concurrent use of opioids, which could contribute to physical findings. Sooklal showed that daily users were more likely to have abdominal pain (43% vs. In looking at those patients who use cannabis, 64% used it daily 20% weekly and 16% monthly. “Hypertensive lower esophageal sphincter with impaired esophageal bolus clearance on manometry with impedance may explain increased heartburn as well as vomiting in cannabis users,” she said. Conversely, more than half of the control group had a normal study and just 20% of cannabis users were classified as normal ( P =. 001) and hypertensive lower esophageal sphincter (27% vs. Using high-resolution esophageal manometry and impedance in 29 patients, Sooklal found that users of cannabis were more likely to have esophageal gastric junction outflow obstruction (40% vs. ![]() “Increased inflammation in cannabis users – esophagitis as well as erosive and non-erosive gastritis – goes against current knowledge where small studies have shown decreased inflammation with cannabis use,” Sooklal said. “Abdominal pain was the most common complaint – not nausea and vomiting as we would have expected,” she said.Įndoscopy findings showed patients using cannabis were more likely to be diagnosed with esophagitis (8% vs. All of these were statistically different from the control group ( P <. 9% in the controls) and nausea and vomiting (7% vs. 8% in the control group), heartburn (15% vs. Sooklal reported that the most frequent symptoms reported by the cannabis group were abdominal pain (25% vs. ![]() Sooklal and colleagues conducted a retrospective chart review of 2,371 patients from 2006 to 2017, using data mining to identify those charts with or without the terms “cannabis” or “marijuana.” They found 772 cannabis users and included 1,599 randomly selected controls for a 2:1 ratio. “These results suggest that cannabis use may potentiate or fail to alleviate a variety of GI complaints, which goes against current knowledge and challenges our knowledge of the interaction of cannabis use and GI symptomology.” This leads to the suggestion that there’s an upper GI tract motility disorder associated with chronic cannabis use possibly similar to the upper GI tract motility disorder associated with opioid use,” S helini Sooklal, MD, of Drexel Medicine, said during her presentation. “Cannabis users were less likely to have a normal manometry study. WASHINGTON - Despite generally accepted ideas that cannabis may be used to reduce inflammation or treat gastrointestinal symptoms, a study presented at Digestive Disease Week 2018 linked regular cannabis use to increased inflammation, abdominal pain and abnormal manometry and endoscopic findings. If you continue to have this issue please contact to Healio ![]()
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